As a result of his grandfather position who was George Shultz, Tyler Shultz managed to get hired at Theranos in the laboratory where he met another fresh graduate named Erika. Together, they tested several times the Edison device to determine the rate of errors. They were surprised to find out that most of the times the device failed to give accurate results.

Soon Tyler found out that Theranos was far from the ideal company he thought they were. He decided to talk about this with his father George because the company asked him to fake the results of the test in order to look like Edison has a low rate of errors. This was considered a fraudulent activity but his father trusted Elizabeth and told him that he he is not experienced enough for such statements and that he should be grateful to work in such a big company. After hearing enough lies, Tyler reached the NY health department where he wrote an anonymous complaint latter. After that, he resigned from his position at Theranos but not before being threatened by Elizabeth that he is on a nondisclosure agreement and that if he tries to hurt her company she will hit back. Soon Erika resigned too after she realized that everything was a scam.